Does AFLIBERCEPT Cause Large intestine perforation? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Large intestine perforation have been filed in association with AFLIBERCEPT (EYLEA). This represents 0.1% of all adverse event reports for AFLIBERCEPT.
13
Reports of Large intestine perforation with AFLIBERCEPT
0.1%
of all AFLIBERCEPT reports
9
Deaths
10
Hospitalizations
How Dangerous Is Large intestine perforation From AFLIBERCEPT?
Of the 13 reports, 9 (69.2%) resulted in death, 10 (76.9%) required hospitalization, and 3 (23.1%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFLIBERCEPT. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does AFLIBERCEPT Cause?
Death (7,669)
Visual impairment (1,836)
Blindness (1,337)
Endophthalmitis (1,289)
Off label use (1,156)
Eye pain (1,057)
Product dose omission issue (1,051)
Blindness unilateral (1,012)
Vision blurred (1,012)
Visual acuity reduced (993)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which AFLIBERCEPT Alternatives Have Lower Large intestine perforation Risk?
AFLIBERCEPT vs AGALSIDASE ALFA
AFLIBERCEPT vs AGALSIDASE BETA
AFLIBERCEPT vs AGOMELATINE
AFLIBERCEPT vs ALAWAY
AFLIBERCEPT vs ALBENDAZOLE