Does ALEMTUZUMAB Cause Agranulocytosis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Agranulocytosis have been filed in association with ALEMTUZUMAB (Campath). This represents 0.1% of all adverse event reports for ALEMTUZUMAB.
15
Reports of Agranulocytosis with ALEMTUZUMAB
0.1%
of all ALEMTUZUMAB reports
3
Deaths
12
Hospitalizations
How Dangerous Is Agranulocytosis From ALEMTUZUMAB?
Of the 15 reports, 3 (20.0%) resulted in death, 12 (80.0%) required hospitalization.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALEMTUZUMAB. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does ALEMTUZUMAB Cause?
Headache (1,808)
Fatigue (1,744)
Pyrexia (1,441)
Off label use (1,259)
Rash (1,094)
Nausea (1,053)
Dyspnoea (855)
Lymphocyte count decreased (852)
Asthenia (841)
Multiple sclerosis relapse (836)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which ALEMTUZUMAB Alternatives Have Lower Agranulocytosis Risk?
ALEMTUZUMAB vs ALENDRONATE
ALEMTUZUMAB vs ALENDRONATE\CHOLECALCIFEROL
ALEMTUZUMAB vs ALENDRONIC ACID
ALEMTUZUMAB vs ALEVE
ALEMTUZUMAB vs ALEVE CAPLET