Does ALENDRONATE\CHOLECALCIFEROL Cause Duodenal ulcer perforation? 627 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 627 reports of Duodenal ulcer perforation have been filed in association with ALENDRONATE\CHOLECALCIFEROL. This represents 24.1% of all adverse event reports for ALENDRONATE\CHOLECALCIFEROL.
627
Reports of Duodenal ulcer perforation with ALENDRONATE\CHOLECALCIFEROL
24.1%
of all ALENDRONATE\CHOLECALCIFEROL reports
448
Deaths
541
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From ALENDRONATE\CHOLECALCIFEROL?
Of the 627 reports, 448 (71.5%) resulted in death, 541 (86.3%) required hospitalization, and 535 (85.3%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALENDRONATE\CHOLECALCIFEROL. However, 627 reports have been filed with the FAERS database.
What Other Side Effects Does ALENDRONATE\CHOLECALCIFEROL Cause?
Fatigue (929)
Arthralgia (841)
Hypertension (820)
Depression (747)
Arthropathy (733)
Rash (726)
Alopecia (711)
Abdominal discomfort (705)
Confusional state (696)
Joint swelling (684)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
LEFLUNOMIDE (4,200)
FOLIC ACID (4,152)
ABATACEPT (4,147)
TOCILIZUMAB (4,130)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
RITUXIMAB (4,081)
PREDNISONE (4,060)
Which ALENDRONATE\CHOLECALCIFEROL Alternatives Have Lower Duodenal ulcer perforation Risk?
ALENDRONATE\CHOLECALCIFEROL vs ALENDRONIC ACID
ALENDRONATE\CHOLECALCIFEROL vs ALEVE
ALENDRONATE\CHOLECALCIFEROL vs ALEVE CAPLET
ALENDRONATE\CHOLECALCIFEROL vs ALEVE LIQUID
ALENDRONATE\CHOLECALCIFEROL vs ALFACALCIDOL