Does ALLOPURINOL Cause Acute hepatic failure? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Acute hepatic failure have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.3% of all adverse event reports for ALLOPURINOL.
49
Reports of Acute hepatic failure with ALLOPURINOL
0.3%
of all ALLOPURINOL reports
15
Deaths
40
Hospitalizations
How Dangerous Is Acute hepatic failure From ALLOPURINOL?
Of the 49 reports, 15 (30.6%) resulted in death, 40 (81.6%) required hospitalization, and 17 (34.7%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which ALLOPURINOL Alternatives Have Lower Acute hepatic failure Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN