Does AMITRIPTYLINE Cause Agranulocytosis? 67 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 67 reports of Agranulocytosis have been filed in association with AMITRIPTYLINE (AMITRIPTYLINE HYDROCHLORIDE). This represents 0.3% of all adverse event reports for AMITRIPTYLINE.
67
Reports of Agranulocytosis with AMITRIPTYLINE
0.3%
of all AMITRIPTYLINE reports
5
Deaths
52
Hospitalizations
How Dangerous Is Agranulocytosis From AMITRIPTYLINE?
Of the 67 reports, 5 (7.5%) resulted in death, 52 (77.6%) required hospitalization, and 32 (47.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for AMITRIPTYLINE.
What Other Side Effects Does AMITRIPTYLINE Cause?
Toxicity to various agents (3,001)
Drug ineffective (2,344)
Completed suicide (1,678)
Off label use (1,588)
Pain (1,300)
Fall (1,216)
Hypotension (1,205)
Drug abuse (1,116)
Dizziness (1,041)
Constipation (1,035)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which AMITRIPTYLINE Alternatives Have Lower Agranulocytosis Risk?
AMITRIPTYLINE vs AMITRIPTYLINE\PERPHENAZINE
AMITRIPTYLINE vs AMIVANTAMAB
AMITRIPTYLINE vs AMIVANTAMAB-VMJW
AMITRIPTYLINE vs AMLODIPINE
AMITRIPTYLINE vs AMLODIPINE BESILATE