Does AMLODIPINE Cause Agranulocytosis? 185 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 185 reports of Agranulocytosis have been filed in association with AMLODIPINE (Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide). This represents 0.3% of all adverse event reports for AMLODIPINE.
185
Reports of Agranulocytosis with AMLODIPINE
0.3%
of all AMLODIPINE reports
9
Deaths
155
Hospitalizations
How Dangerous Is Agranulocytosis From AMLODIPINE?
Of the 185 reports, 9 (4.9%) resulted in death, 155 (83.8%) required hospitalization, and 23 (12.4%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMLODIPINE. However, 185 reports have been filed with the FAERS database.
What Other Side Effects Does AMLODIPINE Cause?
Hypotension (6,504)
Toxicity to various agents (5,554)
Completed suicide (5,267)
Drug ineffective (4,091)
Dyspnoea (3,907)
Dizziness (3,536)
Intentional overdose (3,427)
Fall (3,215)
Fatigue (3,141)
Headache (2,907)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which AMLODIPINE Alternatives Have Lower Agranulocytosis Risk?
AMLODIPINE vs AMLODIPINE BESILATE
AMLODIPINE vs AMLODIPINE\ATORVASTATIN
AMLODIPINE vs AMLODIPINE\BENAZEPRIL
AMLODIPINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN
AMLODIPINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL