Does AMLODIPINE Cause Cardiotoxicity? 182 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 182 reports of Cardiotoxicity have been filed in association with AMLODIPINE (Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide). This represents 0.3% of all adverse event reports for AMLODIPINE.
182
Reports of Cardiotoxicity with AMLODIPINE
0.3%
of all AMLODIPINE reports
30
Deaths
136
Hospitalizations
How Dangerous Is Cardiotoxicity From AMLODIPINE?
Of the 182 reports, 30 (16.5%) resulted in death, 136 (74.7%) required hospitalization, and 78 (42.9%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMLODIPINE. However, 182 reports have been filed with the FAERS database.
What Other Side Effects Does AMLODIPINE Cause?
Hypotension (6,504)
Toxicity to various agents (5,554)
Completed suicide (5,267)
Drug ineffective (4,091)
Dyspnoea (3,907)
Dizziness (3,536)
Intentional overdose (3,427)
Fall (3,215)
Fatigue (3,141)
Headache (2,907)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which AMLODIPINE Alternatives Have Lower Cardiotoxicity Risk?
AMLODIPINE vs AMLODIPINE BESILATE
AMLODIPINE vs AMLODIPINE\ATORVASTATIN
AMLODIPINE vs AMLODIPINE\BENAZEPRIL
AMLODIPINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN
AMLODIPINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL