Does VINCRISTINE Cause Cardiotoxicity? 446 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 446 reports of Cardiotoxicity have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.6% of all adverse event reports for VINCRISTINE.
446
Reports of Cardiotoxicity with VINCRISTINE
0.6%
of all VINCRISTINE reports
112
Deaths
94
Hospitalizations
How Dangerous Is Cardiotoxicity From VINCRISTINE?
Of the 446 reports, 112 (25.1%) resulted in death, 94 (21.1%) required hospitalization, and 27 (6.1%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 446 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
PACLITAXEL (269)
Which VINCRISTINE Alternatives Have Lower Cardiotoxicity Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE