Does RITUXIMAB Cause Cardiotoxicity? 389 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 389 reports of Cardiotoxicity have been filed in association with RITUXIMAB (Rituxan). This represents 0.2% of all adverse event reports for RITUXIMAB.
389
Reports of Cardiotoxicity with RITUXIMAB
0.2%
of all RITUXIMAB reports
111
Deaths
70
Hospitalizations
How Dangerous Is Cardiotoxicity From RITUXIMAB?
Of the 389 reports, 111 (28.5%) resulted in death, 70 (18.0%) required hospitalization, and 26 (6.7%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 389 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
PACLITAXEL (269)
Which RITUXIMAB Alternatives Have Lower Cardiotoxicity Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE