Does TRASTUZUMAB Cause Cardiotoxicity? 950 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 950 reports of Cardiotoxicity have been filed in association with TRASTUZUMAB (Trazimera). This represents 2.0% of all adverse event reports for TRASTUZUMAB.
950
Reports of Cardiotoxicity with TRASTUZUMAB
2.0%
of all TRASTUZUMAB reports
61
Deaths
101
Hospitalizations
How Dangerous Is Cardiotoxicity From TRASTUZUMAB?
Of the 950 reports, 61 (6.4%) resulted in death, 101 (10.6%) required hospitalization, and 29 (3.1%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 950 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
PACLITAXEL (269)
Which TRASTUZUMAB Alternatives Have Lower Cardiotoxicity Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE