Does PACLITAXEL Cause Cardiotoxicity? 269 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 269 reports of Cardiotoxicity have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
269
Reports of Cardiotoxicity with PACLITAXEL
0.4%
of all PACLITAXEL reports
39
Deaths
42
Hospitalizations
How Dangerous Is Cardiotoxicity From PACLITAXEL?
Of the 269 reports, 39 (14.5%) resulted in death, 42 (15.6%) required hospitalization, and 19 (7.1%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 269 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which PACLITAXEL Alternatives Have Lower Cardiotoxicity Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON