Does AMPHOTERICIN B Cause Agranulocytosis? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Agranulocytosis have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.3% of all adverse event reports for AMPHOTERICIN B.
32
Reports of Agranulocytosis with AMPHOTERICIN B
0.3%
of all AMPHOTERICIN B reports
13
Deaths
29
Hospitalizations
How Dangerous Is Agranulocytosis From AMPHOTERICIN B?
Of the 32 reports, 13 (40.6%) resulted in death, 29 (90.6%) required hospitalization, and 11 (34.4%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for AMPHOTERICIN B.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which AMPHOTERICIN B Alternatives Have Lower Agranulocytosis Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA