Does ASPARAGINASE Cause Bone marrow failure? 112 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 112 reports of Bone marrow failure have been filed in association with ASPARAGINASE (Rylaze). This represents 2.2% of all adverse event reports for ASPARAGINASE.
112
Reports of Bone marrow failure with ASPARAGINASE
2.2%
of all ASPARAGINASE reports
33
Deaths
33
Hospitalizations
How Dangerous Is Bone marrow failure From ASPARAGINASE?
Of the 112 reports, 33 (29.5%) resulted in death, 33 (29.5%) required hospitalization, and 32 (28.6%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 112 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which ASPARAGINASE Alternatives Have Lower Bone marrow failure Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE