Does ASPARAGINASE Cause Encephalitis? 59 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 59 reports of Encephalitis have been filed in association with ASPARAGINASE (Rylaze). This represents 1.2% of all adverse event reports for ASPARAGINASE.
59
Reports of Encephalitis with ASPARAGINASE
1.2%
of all ASPARAGINASE reports
16
Deaths
7
Hospitalizations
How Dangerous Is Encephalitis From ASPARAGINASE?
Of the 59 reports, 16 (27.1%) resulted in death, 7 (11.9%) required hospitalization, and 3 (5.1%) were considered life-threatening.
Is Encephalitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 59 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Encephalitis?
NIVOLUMAB (377)
METHOTREXATE (372)
PREDNISONE (365)
PEMBROLIZUMAB (352)
RITUXIMAB (263)
TACROLIMUS (253)
CYCLOPHOSPHAMIDE (244)
ATEZOLIZUMAB (236)
MYCOPHENOLATE MOFETIL (228)
PREDNISOLONE (190)
Which ASPARAGINASE Alternatives Have Lower Encephalitis Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE