Does ATOVAQUONE Cause Agranulocytosis? 69 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 69 reports of Agranulocytosis have been filed in association with ATOVAQUONE (Atovaquone). This represents 3.0% of all adverse event reports for ATOVAQUONE.
69
Reports of Agranulocytosis with ATOVAQUONE
3.0%
of all ATOVAQUONE reports
3
Deaths
45
Hospitalizations
How Dangerous Is Agranulocytosis From ATOVAQUONE?
Of the 69 reports, 3 (4.3%) resulted in death, 45 (65.2%) required hospitalization, and 9 (13.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ATOVAQUONE. However, 69 reports have been filed with the FAERS database.
What Other Side Effects Does ATOVAQUONE Cause?
Off label use (176)
Drug ineffective (164)
Condition aggravated (145)
Thrombocytopenia (127)
Pyrexia (117)
Rash (108)
Neutropenia (89)
Diarrhoea (86)
Pneumocystis jirovecii pneumonia (83)
Product use in unapproved indication (83)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which ATOVAQUONE Alternatives Have Lower Agranulocytosis Risk?
ATOVAQUONE vs ATOVAQUONE\PROGUANIL
ATOVAQUONE vs ATRACURIUM
ATOVAQUONE vs ATRIPLA
ATOVAQUONE vs ATROPINE
ATOVAQUONE vs ATROPINE\ATROPINE