Does BINIMETINIB Cause Hepatic cytolysis? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Hepatic cytolysis have been filed in association with BINIMETINIB (MEKTOVI). This represents 0.6% of all adverse event reports for BINIMETINIB.
40
Reports of Hepatic cytolysis with BINIMETINIB
0.6%
of all BINIMETINIB reports
0
Deaths
21
Hospitalizations
How Dangerous Is Hepatic cytolysis From BINIMETINIB?
Of the 40 reports, 21 (52.5%) required hospitalization, and 2 (5.0%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does BINIMETINIB Cause?
Off label use (902)
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which BINIMETINIB Alternatives Have Lower Hepatic cytolysis Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL