Does BORTEZOMIB Cause Agranulocytosis? 66 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Agranulocytosis have been filed in association with BORTEZOMIB (bortezomib). This represents 0.1% of all adverse event reports for BORTEZOMIB.
66
Reports of Agranulocytosis with BORTEZOMIB
0.1%
of all BORTEZOMIB reports
8
Deaths
24
Hospitalizations
How Dangerous Is Agranulocytosis From BORTEZOMIB?
Of the 66 reports, 8 (12.1%) resulted in death, 24 (36.4%) required hospitalization, and 11 (16.7%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BORTEZOMIB. However, 66 reports have been filed with the FAERS database.
What Other Side Effects Does BORTEZOMIB Cause?
Plasma cell myeloma (6,683)
Off label use (4,754)
Neuropathy peripheral (4,067)
Drug ineffective (2,730)
Diarrhoea (2,244)
Thrombocytopenia (2,082)
Death (2,025)
Pneumonia (2,020)
Fatigue (1,757)
Neutropenia (1,530)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which BORTEZOMIB Alternatives Have Lower Agranulocytosis Risk?
BORTEZOMIB vs BOSENTAN
BORTEZOMIB vs BOSENTAN\BOSENTAN
BORTEZOMIB vs BOSULIF
BORTEZOMIB vs BOSUTINIB
BORTEZOMIB vs BOTOX