Does BUPROPION Cause Cardiotoxicity? 170 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 170 reports of Cardiotoxicity have been filed in association with BUPROPION (Bupropion Hydrochloride (XL)). This represents 0.5% of all adverse event reports for BUPROPION.
170
Reports of Cardiotoxicity with BUPROPION
0.5%
of all BUPROPION reports
18
Deaths
151
Hospitalizations
How Dangerous Is Cardiotoxicity From BUPROPION?
Of the 170 reports, 18 (10.6%) resulted in death, 151 (88.8%) required hospitalization, and 61 (35.9%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPROPION. However, 170 reports have been filed with the FAERS database.
What Other Side Effects Does BUPROPION Cause?
Completed suicide (5,095)
Drug ineffective (3,991)
Toxicity to various agents (3,837)
Depression (2,486)
Overdose (2,357)
Headache (2,323)
Anxiety (2,145)
Intentional overdose (2,103)
Drug hypersensitivity (1,967)
Seizure (1,894)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which BUPROPION Alternatives Have Lower Cardiotoxicity Risk?
BUPROPION vs BUPROPION HYDROBROMIDE
BUPROPION vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPROPION vs BUPROPION\NALTREXONE
BUPROPION vs BUROSUMAB
BUPROPION vs BUROSUMAB-TWZA