Does CANAGLIFLOZIN Cause Hypernatraemia? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Hypernatraemia have been filed in association with CANAGLIFLOZIN (INVOKANA). This represents 0.1% of all adverse event reports for CANAGLIFLOZIN.
18
Reports of Hypernatraemia with CANAGLIFLOZIN
0.1%
of all CANAGLIFLOZIN reports
2
Deaths
14
Hospitalizations
How Dangerous Is Hypernatraemia From CANAGLIFLOZIN?
Of the 18 reports, 2 (11.1%) resulted in death, 14 (77.8%) required hospitalization, and 6 (33.3%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CANAGLIFLOZIN. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does CANAGLIFLOZIN Cause?
Diabetic ketoacidosis (3,413)
Toe amputation (2,193)
Osteomyelitis (2,146)
Acute kidney injury (1,853)
Fungal infection (1,385)
Gangrene (1,081)
Weight decreased (1,014)
Cellulitis (1,007)
Urinary tract infection (920)
Diabetic foot infection (832)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
Which CANAGLIFLOZIN Alternatives Have Lower Hypernatraemia Risk?
CANAGLIFLOZIN vs CANAGLIFLOZIN\METFORMIN
CANAGLIFLOZIN vs CANAKINUMAB
CANAGLIFLOZIN vs CANDESARTAN
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL
CANAGLIFLOZIN vs CANDESARTAN CILEXETIL\HYDROCHLOROTHIAZIDE