Does CHLORPROMAZINE Cause Agranulocytosis? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Agranulocytosis have been filed in association with CHLORPROMAZINE (Chlorpromazine). This represents 1.1% of all adverse event reports for CHLORPROMAZINE.
42
Reports of Agranulocytosis with CHLORPROMAZINE
1.1%
of all CHLORPROMAZINE reports
4
Deaths
27
Hospitalizations
How Dangerous Is Agranulocytosis From CHLORPROMAZINE?
Of the 42 reports, 4 (9.5%) resulted in death, 27 (64.3%) required hospitalization, and 8 (19.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for CHLORPROMAZINE.
What Other Side Effects Does CHLORPROMAZINE Cause?
Drug ineffective (374)
Toxicity to various agents (301)
Off label use (288)
Drug abuse (243)
Overdose (223)
Foetal exposure during pregnancy (190)
Neuroleptic malignant syndrome (186)
Somnolence (170)
Neutropenia (169)
Seizure (164)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which CHLORPROMAZINE Alternatives Have Lower Agranulocytosis Risk?
CHLORPROMAZINE vs CHLORPROTHIXENE
CHLORPROMAZINE vs CHLORTHALIDONE
CHLORPROMAZINE vs CHLORZOXAZONE
CHLORPROMAZINE vs CHOLECALCIFEROL
CHLORPROMAZINE vs CHOLECALCIFEROL\ERGOCALCIFEROL