Does CILASTATIN Cause Agranulocytosis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Agranulocytosis have been filed in association with CILASTATIN (Imipenem and Cilastatin). This represents 6.8% of all adverse event reports for CILASTATIN.
8
Reports of Agranulocytosis with CILASTATIN
6.8%
of all CILASTATIN reports
0
Deaths
8
Hospitalizations
How Dangerous Is Agranulocytosis From CILASTATIN?
Of the 8 reports, 8 (100.0%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for CILASTATIN.
What Other Side Effects Does CILASTATIN Cause?
Vomiting (10)
Drug ineffective (9)
Pyrexia (9)
Eosinophilia (8)
Heparin-induced thrombocytopenia (8)
Hyperbilirubinaemia (8)
Hyponatraemia (8)
Off label use (8)
Diarrhoea (7)
Paraesthesia (7)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which CILASTATIN Alternatives Have Lower Agranulocytosis Risk?
CILASTATIN vs CILASTATIN\IMIPENEM
CILASTATIN vs CILAZAPRIL ANHYDROUS
CILASTATIN vs CILGAVIMAB\TIXAGEVIMAB
CILASTATIN vs CILOSTAZOL
CILASTATIN vs CILTACABTAGENE AUTOLEUCEL