Does CISPLATIN Cause Agranulocytosis? 177 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 177 reports of Agranulocytosis have been filed in association with CISPLATIN (CISplatin). This represents 0.4% of all adverse event reports for CISPLATIN.
177
Reports of Agranulocytosis with CISPLATIN
0.4%
of all CISPLATIN reports
25
Deaths
101
Hospitalizations
How Dangerous Is Agranulocytosis From CISPLATIN?
Of the 177 reports, 25 (14.1%) resulted in death, 101 (57.1%) required hospitalization, and 58 (32.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CISPLATIN. However, 177 reports have been filed with the FAERS database.
What Other Side Effects Does CISPLATIN Cause?
Off label use (4,359)
Disease progression (3,746)
Neutropenia (3,095)
Febrile neutropenia (3,010)
Nausea (2,923)
Drug ineffective (2,608)
Thrombocytopenia (2,565)
Anaemia (2,530)
Vomiting (2,326)
Diarrhoea (2,022)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which CISPLATIN Alternatives Have Lower Agranulocytosis Risk?
CISPLATIN vs CISPLATIN\CYTARABINE\DEXAMETHASONE
CISPLATIN vs CITALOPRAM
CISPLATIN vs CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITALOPRAM\CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITICOLINE