CLOFARABINE for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 160 adverse event reports in the FDA FAERS database where CLOFARABINE was used for Bone marrow conditioning regimen.
Most Reported Side Effects for CLOFARABINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 201 | 14.2% | 57 | 85 |
| Off label use | 158 | 11.1% | 78 | 39 |
| Drug ineffective | 139 | 9.8% | 43 | 33 |
| Pyrexia | 139 | 9.8% | 25 | 50 |
| Mucosal inflammation | 89 | 6.3% | 13 | 5 |
| Sepsis | 85 | 6.0% | 46 | 24 |
| Alanine aminotransferase increased | 82 | 5.8% | 14 | 18 |
| Acute kidney injury | 80 | 5.6% | 54 | 20 |
| Multiple organ dysfunction syndrome | 77 | 5.4% | 72 | 25 |
| Aspartate aminotransferase increased | 76 | 5.4% | 13 | 15 |
| Neutropenia | 76 | 5.4% | 24 | 19 |
| Pancytopenia | 69 | 4.9% | 27 | 23 |
| Haematotoxicity | 67 | 4.7% | 10 | 1 |
| Product use in unapproved indication | 66 | 4.7% | 23 | 16 |
| Bone marrow failure | 63 | 4.4% | 37 | 13 |
Other Indications for CLOFARABINE
Acute myeloid leukaemia (357)
Acute lymphocytic leukaemia (323)
Acute lymphocytic leukaemia recurrent (71)
Chemotherapy (48)
Product used for unknown indication (43)
Langerhans' cell histiocytosis (37)
B precursor type acute leukaemia (35)
Allogenic stem cell transplantation (31)
Stem cell transplant (26)
Acute lymphocytic leukaemia refractory (25)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
MELPHALAN (2,368)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
THIOTEPA (1,551)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)