CLOFARABINE for Stem cell transplant: Side Effects & Safety Data
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There are 26 adverse event reports in the FDA FAERS database where CLOFARABINE was used for Stem cell transplant.
Most Reported Side Effects for CLOFARABINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 201 | 14.2% | 57 | 85 |
| Off label use | 158 | 11.1% | 78 | 39 |
| Drug ineffective | 139 | 9.8% | 43 | 33 |
| Pyrexia | 139 | 9.8% | 25 | 50 |
| Mucosal inflammation | 89 | 6.3% | 13 | 5 |
| Sepsis | 85 | 6.0% | 46 | 24 |
| Alanine aminotransferase increased | 82 | 5.8% | 14 | 18 |
| Acute kidney injury | 80 | 5.6% | 54 | 20 |
| Multiple organ dysfunction syndrome | 77 | 5.4% | 72 | 25 |
| Aspartate aminotransferase increased | 76 | 5.4% | 13 | 15 |
| Neutropenia | 76 | 5.4% | 24 | 19 |
| Pancytopenia | 69 | 4.9% | 27 | 23 |
| Haematotoxicity | 67 | 4.7% | 10 | 1 |
| Product use in unapproved indication | 66 | 4.7% | 23 | 16 |
| Bone marrow failure | 63 | 4.4% | 37 | 13 |
Other Indications for CLOFARABINE
Acute myeloid leukaemia (357)
Acute lymphocytic leukaemia (323)
Bone marrow conditioning regimen (160)
Acute lymphocytic leukaemia recurrent (71)
Chemotherapy (48)
Product used for unknown indication (43)
Langerhans' cell histiocytosis (37)
B precursor type acute leukaemia (35)
Allogenic stem cell transplantation (31)
Acute lymphocytic leukaemia refractory (25)
Other Drugs Used for Stem cell transplant
BUSULFAN (1,700)
FLUDARABINE (1,601)
CYCLOPHOSPHAMIDE (1,262)
CYCLOSPORINE (1,251)
MYCOPHENOLATE MOFETIL (938)
THIOTEPA (799)
MELPHALAN (738)
TACROLIMUS (600)
METHOTREXATE (481)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (442)