Does CYCLOPHOSPHAMIDE Cause Hepatotoxicity? 632 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 632 reports of Hepatotoxicity have been filed in association with CYCLOPHOSPHAMIDE (Cyclophosphamide). This represents 0.5% of all adverse event reports for CYCLOPHOSPHAMIDE.
632
Reports of Hepatotoxicity with CYCLOPHOSPHAMIDE
0.5%
of all CYCLOPHOSPHAMIDE reports
98
Deaths
155
Hospitalizations
How Dangerous Is Hepatotoxicity From CYCLOPHOSPHAMIDE?
Of the 632 reports, 98 (15.5%) resulted in death, 155 (24.5%) required hospitalization, and 72 (11.4%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for CYCLOPHOSPHAMIDE.
What Other Side Effects Does CYCLOPHOSPHAMIDE Cause?
Off label use (12,578)
Febrile neutropenia (11,318)
Drug ineffective (8,142)
Neutropenia (7,352)
Disease progression (7,100)
Pyrexia (6,126)
Product use in unapproved indication (5,750)
Thrombocytopenia (4,669)
Pneumonia (4,595)
Nausea (4,561)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
SULFASALAZINE (613)
RIBOCICLIB (585)
Which CYCLOPHOSPHAMIDE Alternatives Have Lower Hepatotoxicity Risk?
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE FOR , USP
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\RITUXIMAB\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOSERINE
CYCLOPHOSPHAMIDE vs CYCLOSPORINE