Does LEFLUNOMIDE Cause Hepatotoxicity? 829 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 829 reports of Hepatotoxicity have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 1.5% of all adverse event reports for LEFLUNOMIDE.
829
Reports of Hepatotoxicity with LEFLUNOMIDE
1.5%
of all LEFLUNOMIDE reports
22
Deaths
174
Hospitalizations
How Dangerous Is Hepatotoxicity From LEFLUNOMIDE?
Of the 829 reports, 22 (2.7%) resulted in death, 174 (21.0%) required hospitalization, and 48 (5.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for LEFLUNOMIDE.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
RIBOCICLIB (585)
Which LEFLUNOMIDE Alternatives Have Lower Hepatotoxicity Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM