Does RITUXIMAB Cause Hepatotoxicity? 702 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 702 reports of Hepatotoxicity have been filed in association with RITUXIMAB (Rituxan). This represents 0.4% of all adverse event reports for RITUXIMAB.
702
Reports of Hepatotoxicity with RITUXIMAB
0.4%
of all RITUXIMAB reports
77
Deaths
211
Hospitalizations
How Dangerous Is Hepatotoxicity From RITUXIMAB?
Of the 702 reports, 77 (11.0%) resulted in death, 211 (30.1%) required hospitalization, and 46 (6.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 702 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
RIBOCICLIB (585)
Which RITUXIMAB Alternatives Have Lower Hepatotoxicity Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE