Does CYTARABINE Cause Agranulocytosis? 297 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 297 reports of Agranulocytosis have been filed in association with CYTARABINE (cytarabine). This represents 0.7% of all adverse event reports for CYTARABINE.
297
Reports of Agranulocytosis with CYTARABINE
0.7%
of all CYTARABINE reports
24
Deaths
169
Hospitalizations
How Dangerous Is Agranulocytosis From CYTARABINE?
Of the 297 reports, 24 (8.1%) resulted in death, 169 (56.9%) required hospitalization, and 53 (17.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 297 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which CYTARABINE Alternatives Have Lower Agranulocytosis Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB