Does DIVALPROEX Cause Agranulocytosis? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Agranulocytosis have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 0.4% of all adverse event reports for DIVALPROEX.
40
Reports of Agranulocytosis with DIVALPROEX
0.4%
of all DIVALPROEX reports
3
Deaths
30
Hospitalizations
How Dangerous Is Agranulocytosis From DIVALPROEX?
Of the 40 reports, 3 (7.5%) resulted in death, 30 (75.0%) required hospitalization, and 25 (62.5%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for DIVALPROEX.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which DIVALPROEX Alternatives Have Lower Agranulocytosis Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS