Does DOXORUBICIN Cause Agranulocytosis? 406 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 406 reports of Agranulocytosis have been filed in association with DOXORUBICIN (Doxorubicin Hydrochloride). This represents 0.5% of all adverse event reports for DOXORUBICIN.
406
Reports of Agranulocytosis with DOXORUBICIN
0.5%
of all DOXORUBICIN reports
45
Deaths
251
Hospitalizations
How Dangerous Is Agranulocytosis From DOXORUBICIN?
Of the 406 reports, 45 (11.1%) resulted in death, 251 (61.8%) required hospitalization, and 146 (36.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOXORUBICIN. However, 406 reports have been filed with the FAERS database.
What Other Side Effects Does DOXORUBICIN Cause?
Febrile neutropenia (8,844)
Off label use (7,858)
Disease progression (6,165)
Neutropenia (5,891)
Drug ineffective (4,598)
Pyrexia (3,697)
Thrombocytopenia (3,638)
Anaemia (3,601)
Product use in unapproved indication (3,502)
Nausea (2,925)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which DOXORUBICIN Alternatives Have Lower Agranulocytosis Risk?
DOXORUBICIN vs DOXYCYCLINE
DOXORUBICIN vs DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYCYCLINE\DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYLAMINE
DOXORUBICIN vs DOXYLAMINE\PYRIDOXINE