Does EPLERENONE Cause Hepatic failure? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Hepatic failure have been filed in association with EPLERENONE (Inspra). This represents 0.2% of all adverse event reports for EPLERENONE.
7
Reports of Hepatic failure with EPLERENONE
0.2%
of all EPLERENONE reports
2
Deaths
6
Hospitalizations
How Dangerous Is Hepatic failure From EPLERENONE?
Of the 7 reports, 2 (28.6%) resulted in death, 6 (85.7%) required hospitalization, and 1 (14.3%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for EPLERENONE. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does EPLERENONE Cause?
Acute kidney injury (570)
Hypotension (398)
Dyspnoea (395)
Cardiac failure (338)
Oedema peripheral (268)
Dizziness (248)
Hyperkalaemia (248)
Drug ineffective (244)
Fatigue (202)
Off label use (188)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which EPLERENONE Alternatives Have Lower Hepatic failure Risk?
EPLERENONE vs EPLONTERSEN
EPLERENONE vs EPOETIN ALFA-EPBX
EPLERENONE vs EPOGEN
EPLERENONE vs EPOPROSTENOL
EPLERENONE vs EPTIFIBATIDE