Does ETOPOSIDE Cause Agranulocytosis? 299 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 299 reports of Agranulocytosis have been filed in association with ETOPOSIDE (Avopef). This represents 0.6% of all adverse event reports for ETOPOSIDE.
299
Reports of Agranulocytosis with ETOPOSIDE
0.6%
of all ETOPOSIDE reports
58
Deaths
176
Hospitalizations
How Dangerous Is Agranulocytosis From ETOPOSIDE?
Of the 299 reports, 58 (19.4%) resulted in death, 176 (58.9%) required hospitalization, and 88 (29.4%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 299 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which ETOPOSIDE Alternatives Have Lower Agranulocytosis Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS