Does FILGRASTIM Cause Agranulocytosis? 74 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 74 reports of Agranulocytosis have been filed in association with FILGRASTIM (NYPOZI txid). This represents 0.5% of all adverse event reports for FILGRASTIM.
74
Reports of Agranulocytosis with FILGRASTIM
0.5%
of all FILGRASTIM reports
8
Deaths
36
Hospitalizations
How Dangerous Is Agranulocytosis From FILGRASTIM?
Of the 74 reports, 8 (10.8%) resulted in death, 36 (48.6%) required hospitalization, and 23 (31.1%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FILGRASTIM. However, 74 reports have been filed with the FAERS database.
What Other Side Effects Does FILGRASTIM Cause?
Off label use (1,930)
Febrile neutropenia (1,570)
Neutropenia (1,431)
Death (1,213)
Pyrexia (1,085)
Diarrhoea (739)
Nausea (718)
Bone pain (706)
Thrombocytopenia (697)
Anaemia (626)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which FILGRASTIM Alternatives Have Lower Agranulocytosis Risk?
FILGRASTIM vs FILGRASTIM-AAFI
FILGRASTIM vs FILGRASTIM-SNDZ
FILGRASTIM vs FINASTERIDE
FILGRASTIM vs FINASTERIDE\TAMSULOSIN
FILGRASTIM vs FINERENONE