Does IBRUTINIB Cause Cardiotoxicity? 100 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 100 reports of Cardiotoxicity have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
100
Reports of Cardiotoxicity with IBRUTINIB
0.1%
of all IBRUTINIB reports
16
Deaths
11
Hospitalizations
How Dangerous Is Cardiotoxicity From IBRUTINIB?
Of the 100 reports, 16 (16.0%) resulted in death, 11 (11.0%) required hospitalization, and 4 (4.0%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 100 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which IBRUTINIB Alternatives Have Lower Cardiotoxicity Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE