Does IFOSFAMIDE Cause Agranulocytosis? 83 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 83 reports of Agranulocytosis have been filed in association with IFOSFAMIDE (IFEX). This represents 0.5% of all adverse event reports for IFOSFAMIDE.
83
Reports of Agranulocytosis with IFOSFAMIDE
0.5%
of all IFOSFAMIDE reports
16
Deaths
54
Hospitalizations
How Dangerous Is Agranulocytosis From IFOSFAMIDE?
Of the 83 reports, 16 (19.3%) resulted in death, 54 (65.1%) required hospitalization, and 34 (41.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for IFOSFAMIDE.
What Other Side Effects Does IFOSFAMIDE Cause?
Off label use (2,281)
Febrile neutropenia (2,225)
Disease progression (1,912)
Neutropenia (1,509)
Drug ineffective (1,331)
Thrombocytopenia (1,227)
Anaemia (1,067)
Product use in unapproved indication (890)
Pyrexia (752)
Sepsis (712)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which IFOSFAMIDE Alternatives Have Lower Agranulocytosis Risk?
IFOSFAMIDE vs IGURATIMOD
IFOSFAMIDE vs ILOPERIDONE
IFOSFAMIDE vs ILOPROST
IFOSFAMIDE vs IMATINIB
IFOSFAMIDE vs IMBRUVICA