Does IRINOTECAN Cause Acute hepatic failure? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Acute hepatic failure have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
17
Reports of Acute hepatic failure with IRINOTECAN
0.1%
of all IRINOTECAN reports
5
Deaths
12
Hospitalizations
How Dangerous Is Acute hepatic failure From IRINOTECAN?
Of the 17 reports, 5 (29.4%) resulted in death, 12 (70.6%) required hospitalization, and 4 (23.5%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which IRINOTECAN Alternatives Have Lower Acute hepatic failure Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE