Does IRINOTECAN Cause Hyperbilirubinaemia? 132 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 132 reports of Hyperbilirubinaemia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.5% of all adverse event reports for IRINOTECAN.
132
Reports of Hyperbilirubinaemia with IRINOTECAN
0.5%
of all IRINOTECAN reports
17
Deaths
37
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From IRINOTECAN?
Of the 132 reports, 17 (12.9%) resulted in death, 37 (28.0%) required hospitalization, and 8 (6.1%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 132 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which IRINOTECAN Alternatives Have Lower Hyperbilirubinaemia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE