Does LAMOTRIGINE Cause Agranulocytosis? 118 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 118 reports of Agranulocytosis have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.3% of all adverse event reports for LAMOTRIGINE.
118
Reports of Agranulocytosis with LAMOTRIGINE
0.3%
of all LAMOTRIGINE reports
14
Deaths
53
Hospitalizations
How Dangerous Is Agranulocytosis From LAMOTRIGINE?
Of the 118 reports, 14 (11.9%) resulted in death, 53 (44.9%) required hospitalization, and 24 (20.3%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for LAMOTRIGINE.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which LAMOTRIGINE Alternatives Have Lower Agranulocytosis Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM