Does LAMOTRIGINE Cause Cardiotoxicity? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Cardiotoxicity have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.1% of all adverse event reports for LAMOTRIGINE.
41
Reports of Cardiotoxicity with LAMOTRIGINE
0.1%
of all LAMOTRIGINE reports
6
Deaths
30
Hospitalizations
How Dangerous Is Cardiotoxicity From LAMOTRIGINE?
Of the 41 reports, 6 (14.6%) resulted in death, 30 (73.2%) required hospitalization, and 15 (36.6%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which LAMOTRIGINE Alternatives Have Lower Cardiotoxicity Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM