Does LAMOTRIGINE Cause Duodenal ulcer perforation? 553 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 553 reports of Duodenal ulcer perforation have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 1.2% of all adverse event reports for LAMOTRIGINE.
553
Reports of Duodenal ulcer perforation with LAMOTRIGINE
1.2%
of all LAMOTRIGINE reports
553
Deaths
468
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From LAMOTRIGINE?
Of the 553 reports, 553 (100.0%) resulted in death, 468 (84.6%) required hospitalization, and 478 (86.4%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 553 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
LEFLUNOMIDE (4,200)
FOLIC ACID (4,152)
ABATACEPT (4,147)
TOCILIZUMAB (4,130)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
RITUXIMAB (4,081)
PREDNISONE (4,060)
Which LAMOTRIGINE Alternatives Have Lower Duodenal ulcer perforation Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM