Does LEFLUNOMIDE Cause Agranulocytosis? 39 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 39 reports of Agranulocytosis have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.1% of all adverse event reports for LEFLUNOMIDE.
39
Reports of Agranulocytosis with LEFLUNOMIDE
0.1%
of all LEFLUNOMIDE reports
4
Deaths
29
Hospitalizations
How Dangerous Is Agranulocytosis From LEFLUNOMIDE?
Of the 39 reports, 4 (10.3%) resulted in death, 29 (74.4%) required hospitalization, and 12 (30.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for LEFLUNOMIDE.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which LEFLUNOMIDE Alternatives Have Lower Agranulocytosis Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM