Does LETROZOLE Cause Agranulocytosis? 43 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 43 reports of Agranulocytosis have been filed in association with LETROZOLE (Letrozole). This represents 0.1% of all adverse event reports for LETROZOLE.
43
Reports of Agranulocytosis with LETROZOLE
0.1%
of all LETROZOLE reports
0
Deaths
20
Hospitalizations
How Dangerous Is Agranulocytosis From LETROZOLE?
Of the 43 reports, 20 (46.5%) required hospitalization, and 12 (27.9%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 43 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which LETROZOLE Alternatives Have Lower Agranulocytosis Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL