Does MELPHALAN Cause Hypercalcaemia? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Hypercalcaemia have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.2% of all adverse event reports for MELPHALAN.
33
Reports of Hypercalcaemia with MELPHALAN
0.2%
of all MELPHALAN reports
6
Deaths
15
Hospitalizations
How Dangerous Is Hypercalcaemia From MELPHALAN?
Of the 33 reports, 6 (18.2%) resulted in death, 15 (45.5%) required hospitalization, and 3 (9.1%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
DENOSUMAB (599)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
Which MELPHALAN Alternatives Have Lower Hypercalcaemia Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL