Does MELPHALAN Cause Polyneuropathy? 174 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 174 reports of Polyneuropathy have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 1.1% of all adverse event reports for MELPHALAN.
174
Reports of Polyneuropathy with MELPHALAN
1.1%
of all MELPHALAN reports
4
Deaths
17
Hospitalizations
How Dangerous Is Polyneuropathy From MELPHALAN?
Of the 174 reports, 4 (2.3%) resulted in death, 17 (9.8%) required hospitalization, and 2 (1.1%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 174 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which MELPHALAN Alternatives Have Lower Polyneuropathy Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL