Does MERCAPTOPURINE Cause Agranulocytosis? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Agranulocytosis have been filed in association with MERCAPTOPURINE (Mercaptopurine). This represents 0.2% of all adverse event reports for MERCAPTOPURINE.
20
Reports of Agranulocytosis with MERCAPTOPURINE
0.2%
of all MERCAPTOPURINE reports
1
Deaths
11
Hospitalizations
How Dangerous Is Agranulocytosis From MERCAPTOPURINE?
Of the 20 reports, 1 (5.0%) resulted in death, 11 (55.0%) required hospitalization, and 1 (5.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MERCAPTOPURINE. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does MERCAPTOPURINE Cause?
Febrile neutropenia (1,853)
Off label use (893)
Pyrexia (855)
Drug ineffective (721)
Vomiting (488)
Neutropenia (485)
Nausea (418)
Pneumonia (394)
Pancytopenia (392)
Sepsis (389)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which MERCAPTOPURINE Alternatives Have Lower Agranulocytosis Risk?
MERCAPTOPURINE vs MEROPENEM
MERCAPTOPURINE vs MEROPENEM ANHYDROUS
MERCAPTOPURINE vs MESALAMINE
MERCAPTOPURINE vs MESNA
MERCAPTOPURINE vs METAMIZOLE