Does MESNA Cause Bone marrow failure? 50 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 50 reports of Bone marrow failure have been filed in association with MESNA (mesna). This represents 1.0% of all adverse event reports for MESNA.
50
Reports of Bone marrow failure with MESNA
1.0%
of all MESNA reports
11
Deaths
30
Hospitalizations
How Dangerous Is Bone marrow failure From MESNA?
Of the 50 reports, 11 (22.0%) resulted in death, 30 (60.0%) required hospitalization, and 4 (8.0%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 50 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which MESNA Alternatives Have Lower Bone marrow failure Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE