Does MESNA Cause Drug resistance? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Drug resistance have been filed in association with MESNA (mesna). This represents 0.3% of all adverse event reports for MESNA.
12
Reports of Drug resistance with MESNA
0.3%
of all MESNA reports
4
Deaths
3
Hospitalizations
How Dangerous Is Drug resistance From MESNA?
Of the 12 reports, 4 (33.3%) resulted in death, 3 (25.0%) required hospitalization, and 6 (50.0%) were considered life-threatening.
Is Drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Drug resistance?
LAMIVUDINE (1,889)
IMATINIB (1,293)
GEFITINIB (1,228)
OSIMERTINIB (1,026)
NEVIRAPINE (862)
PREDNISONE (833)
CYCLOPHOSPHAMIDE (817)
LEVETIRACETAM (798)
METHOTREXATE (765)
TENOFOVIR DISOPROXIL (740)
Which MESNA Alternatives Have Lower Drug resistance Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE