Does MESNA Cause Febrile bone marrow aplasia? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Febrile bone marrow aplasia have been filed in association with MESNA (mesna). This represents 1.1% of all adverse event reports for MESNA.
54
Reports of Febrile bone marrow aplasia with MESNA
1.1%
of all MESNA reports
17
Deaths
35
Hospitalizations
How Dangerous Is Febrile bone marrow aplasia From MESNA?
Of the 54 reports, 17 (31.5%) resulted in death, 35 (64.8%) required hospitalization, and 10 (18.5%) were considered life-threatening.
Is Febrile bone marrow aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Febrile bone marrow aplasia?
VINCRISTINE (912)
METHOTREXATE (880)
CYCLOPHOSPHAMIDE (839)
CYTARABINE (733)
PEGASPARGASE (668)
DOXORUBICIN (623)
DEXAMETHASONE (555)
CARBOPLATIN (440)
ETOPOSIDE (413)
HYDROCORTISONE (379)
Which MESNA Alternatives Have Lower Febrile bone marrow aplasia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE