Does METHOTREXATE Cause Febrile bone marrow aplasia? 880 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 880 reports of Febrile bone marrow aplasia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
880
Reports of Febrile bone marrow aplasia with METHOTREXATE
0.4%
of all METHOTREXATE reports
49
Deaths
770
Hospitalizations
How Dangerous Is Febrile bone marrow aplasia From METHOTREXATE?
Of the 880 reports, 49 (5.6%) resulted in death, 770 (87.5%) required hospitalization, and 84 (9.5%) were considered life-threatening.
Is Febrile bone marrow aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 880 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Febrile bone marrow aplasia?
VINCRISTINE (912)
CYCLOPHOSPHAMIDE (839)
CYTARABINE (733)
PEGASPARGASE (668)
DOXORUBICIN (623)
DEXAMETHASONE (555)
CARBOPLATIN (440)
ETOPOSIDE (413)
HYDROCORTISONE (379)
RITUXIMAB (313)
Which METHOTREXATE Alternatives Have Lower Febrile bone marrow aplasia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA