Does MESNA Cause Hepatitis? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Hepatitis have been filed in association with MESNA (mesna). This represents 0.5% of all adverse event reports for MESNA.
24
Reports of Hepatitis with MESNA
0.5%
of all MESNA reports
12
Deaths
3
Hospitalizations
How Dangerous Is Hepatitis From MESNA?
Of the 24 reports, 12 (50.0%) resulted in death, 3 (12.5%) required hospitalization, and 3 (12.5%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
Yes, Hepatitis is listed as a known adverse reaction in the official FDA drug label for MESNA.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which MESNA Alternatives Have Lower Hepatitis Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE